Contrasting Roles of Mitogen - activated Protein Kinases in Cellular Entry and Replication 2 of Hepatitis C Virus : MKNK 1 Facilitates Cell Entry
نویسندگان
چکیده
Division of Infectious Diseases, Department of Medicine, and the Lineberger Comprehensive 10 Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7292; 11 Department of Microbiology and Immunology, University of Texas Medical Branch, 12 Galveston, TX 77555-7030, USA; Biochemical Pharmacology, Virology DBA, Roche Palo 13 Alto, 3431 Hillview Ave, Palo Alto, CA 94304, USA; Department of Pathology, Stanford 14 University School of Medicine, Stanford, CA 94305, USA. 15 16
منابع مشابه
Contrasting roles of mitogen-activated protein kinases in cellular entry and replication of hepatitis C virus: MKNK1 facilitates cell entry.
The human kinome comprises over 800 individual kinases. These contribute in multiple ways to regulation of cellular metabolism and may have direct and indirect effects on virus replication. Kinases are tempting therapeutic targets for drug development, but achieving sufficient specificity is often a challenge for chemical inhibitors. While using inhibitors to assess whether c-Jun N-terminal (JN...
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تاریخ انتشار 2013